Vitamin B12 deficiency symptoms: The sign in your vision you could be lacking B12

Vitamin B12 deficiency occurs when the autoimmune system attacks cells in the stomach – named pernicious anaemia. There’s a sign in your vision that you could be lacking the nutrient.

Inside the stomach there’s a protein called intrinsic factor.

Someone suffering from pernicious anaemia has an immune system that attacks cells in the stomach.

Specifically, the immune system targets cells that are responsible for making intrinsic factor.

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Usually, intrinsic factor combines with vitamin B12 – sourced from food – and travels to a part of the gut called the distal ileum.

Here, the mixture of vitamin B12 and intrinsic factor is absorbed into the body.

This enables the nutrient to benefit the body’s red blood cells, nerve cells and DNA.

With pernicious anaemia, this doesn’t happen – instead, prolonged absence of vitamin B12 leads to symptoms.

Researchers from Mahidol University, Thailand, did a case study on a young man who had some of his bowel removed.

Having suffered from gangrene at a young age, the boy had his parts of his bowel – including the ileum – cut out at 11 years old.

At the time of the study, the 19-year-old has low levels of vitamin B12 in his body.

This would make sense, as the part of the bowel where vitamin B12 is usually absorbed – the ileum – had been cut out.

He also had less than the normal number of cells in his bone marrow – called hypocellular – and the bone marrow is where red blood cells are created.

He had complained of blurred vision and his visual acuity was 5/200.

Treatment was intramuscular injections of 1,000 micrograms of cyanocobalamin – a man-made form of vitamin B12.

Four months later, the man’s visual acuity improved, as did his levels of vitamin B12 and the bone marrow returned to normal functioning.

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The researchers concluded: “This is a frank case of optic neuropathy in a patient with vitamin B12 deficiency due to a massive small bowel resection.”

Symptoms of vitamin B12 deficiency

The NHS confirms “disturbed vision” is one symptom caused by a vitamin B12 deficiency.

Others include depression, irritability, and changes in the way you walk and move around.

Additionally, some people may experience mouth ulcers, pins and needles, and a pale yellow tinge to the skin.

Treatment

Treatment for a vitamin B12 deficiency is injections of man-made versions of the nutrient.

This would either be hydroxocobalamin or cyanocobalamin – the latter was the treatment option for the boy in the case study.

In the UK, hydroxocobalamin is the recommended option as it stays in the body for longer.

These injections will be administered by a medical professional, such as a nurse or doctor.

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Calvin Harris Says His Heart Stopped in 2014: 'Interesting Year for Me'


Calvin Harris needed lifesaving help in 2014 after his heart stopped.

The DJ and singer revealed on Twitter that he had to have his heart “restarted” in the emergency room.

Harris retweeted a video on Tuesday night from his June 2014 performance at the Electric Daisy Festival, and added that it was an “interesting year.”

“Started with me knocking myself off number 1 in the UK and ended with my heart getting restarted in the ER…this sort of stuff happened in between,” he said.

Harris had hinted at his condition that year, but hadn’t previously said that his heart had stopped. Rather, the “Slide” singer said that he had “some heart problems” that needed to “be fixed” and were the reason why he canceled several shows.

He later clarified that he had an arrythmia, a heart condition that causes an irregular heartbeat and can lead to chest pain, fainting and dizziness.

That pushed him to give up drinking, he said on Twitter in 2018.

“Haven't drank in 4 years big man,” Harris told a fan who asked why he was abstaining from alcohol. "Aye things are a bit less fun but haven't had an arrhythmia since 2014.”

But Harris said he’s happy with the decision.

“The last thing I want to do is down 2 bottles of jack daniels a night, live on greggs pasties and sleep on an absolutely stinking bus all year, scream down a mic for 55 minutes and pretend to play a keyboard 5x a week those days are behind me son,” he added to the fan.

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Britain faces ‘calamitous consequences’ as expert warns UK faces more deaths than in WW2

A new study – the first of its kind – shows that chasing an infection target of below 1 will force Britons into long term social distancing and more lockdowns. 

It shows that without a vaccine, it would take until December 2024 to see off the virus using social distancing.

But the economic cost of these measures would be so grave it would kill more people than WWII, Philip Thomas, a Professor of Risk Management at the University of Bristol has found.

The study estimated that 150,000 people will die from Covid-19 over five years under intermittent lockdown or semi-lockdown conditions that would be necessary to keep infection rates at the government goal close to below 

The analysis, shortly to be published in the Scientific Journal Nanotechnology Perceptions, was based on projected death rates linked to the virus, together with the economic impact of social distancing or lockdown and that of previous recessions. It shows “calamitous” long term consequences leading to large scale loss of life.

It reveals a move out of lockdown slow enough to avoid a strain on the NHS due to a surge in cases is likely to cause a drop of 23.5 percent to the economy in 2020 and still further in 2021. The study also reveals the economy would not return to pre-lockdown levels until the end of 2024. This would cause a dramatic cost to health and an associated loss of an extra 675,000 lives due to poor healthcare and impoverishment, as well as a relaxation of safety regulations.

This is higher than the UK’s loss of life over the six years of the Second World War which equated to approximately 525,000 civilian and military personnel, dwarfing the number of lives saved by lockdown.

Professor Thomas said: “It is not enough to look at the epidemiology, the spread of Covid-19, in isolation. You need to look just as much as the effect on the economy because a nation’s economy and its health are so strongly linked that at some point they become inseparable. Poverty kills just as surely as the coronavirus. The only reason we have good health and live a long time in the UK is because we are one of the wealthiest nations in the world. The policy of coming out of lockdown gradually, over five years – which will be necessary if we are to keep the infection rate close to or below 1 – will reduce the toll on life from the coronavirus but incur a far greater loss of life through the impoverishment of the nation. The net loss of life is likely to be of the order of 675,000 lives.

“The initial pandemic response to lockdown as a device for gaining time to build defences and make sure our health service was not overwhelmed was a reasonable response. But our society cannot remain under siege forever and we need to find a way of returning towards normality.

“I think we can more or less justify a lockdown of two months based on the ill effects to the economy but three months is too long. We now have to realise if we do go so slowly and continue with the aim to keep the infection rate close to or below one then the number of deaths from the prolonged lockdown will be far worse and we will be condemning people to significant impoverishment, permanent loss of wealth and more deaths than lives saved and we have to ask ourselves: “What are we doing?”

He added: “We are faced with a bad situation where there are no easy wins. We cannot just gamble on waiting for a vaccine as we cannot rely on this. This is not just a question of saving people’s money versus saving people’s lives. It is comparing life versus life.”

He also pointed out that the case against coming out of the lockdown slowly was even stronger if, as various studies have pointed out, the number of people who have already had infections is far higher than current estimates which would mean the virus is less lethal than previously thought.

Professor Thomas said he supported the less draconian social distancing measures followed by Sweden which he said were “broadly sensible.”

He added: “Lockdown doesn’t do much and does not get rid of the virus – it only gives you time.”

His comments follow criticism of the UK lockdown system by former chief scientist at the European Centre for Disease Control, Professor Johan Giesecke. Professor Giesecke, who has been advising the Swedish Agency for Public Health said in a recent article in The Lancet: “Everyone will be exposed to severe acute respiratory syndrome coronavirus and most people will become infected. COVID-19 is spreading like wildfire in all countries, but we do not see it – it almost always spreads from younger people with no or weak symptoms to other people who will also have mild symptoms. This is the real pandemic, but it goes on beneath the surface, and is probably at its peak now in many European countries. There is very little we can do to prevent this spread: a lockdown might delay severe cases for a while, but once restrictions are eased, cases will reappear. I expect that when we count the number of deaths from COVID-19 in each country in 1 year from now, the figures will be similar, regardless of measures taken.”

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Heart attack: Worst food group which significantly raises your risk

Heart attacks occur when the supply of blood to the heart is suddenly blocked. A lack of blood to the heart may seriously damage the heart muscle and can prove deadly. When it comes to one’s diet, aiming for five portions of fruits and vegetables will help to keep the heart healthy. When it comes to a food which does the opposite, there is one that should be avoided as much as possible.

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When a heart attack occurs, it can disrupt a person’s normal heart rhythm, potentially stopping it altogether.

When the heart stops getting a supply of blood during a heart attack, some of the tissue can die.

This can weaken the heart and later cause life-threatening conditions such as heart failure.

Heart attacks can affect the heart valve and cause leaks.

Keeping healthy and active are some of the best methods to reduce having a heart attack and spotting early signs is also crucial.

When it comes to being healthy and reducing your risk of serious conditions, eating bacon should be avoided.

More than half of bacon’s calories come from saturated fat.

Saturated fat raises the low-density lipoprotein (LDL) or bad cholesterol and boost the chance of a heart attack or stroke.

Bacon also contains high amounts of salt which bumps up the blood pressure and makes the heart work harder.

High amounts of sodium can lead to stroke, heart disease and heart failure.

Bacon’s added preservatives are linked to these issues as well.

A study of almost 30,000 people followed for up to three decades found those who regularly consumed processed meat such as bacon were more prone to premature death.

In particular, having red or processed meat every seven days was linked to a three percent to seven percent higher risk of cardiovascular disease.

Senior author of the study, Norrina Allen, professor of preventative medicine at Northwestern University, Chicago said: “It is a small difference, but it’s worth trying to reduce red meat and processed meat like pepperoni and deli meats.

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Red meat includes beef, lamb, pork, veal and venison.

Processed is bacon, sausages, hot dogs, salami and corned beef.

The study published in JAMA Internal Medicine included self-reported diets over the previous year or month of 29,682 men and women with an average age of 53.

Lead author Dr Victor Zhong said: “Modifying intake of these animal protein foods may be an important strategy to help reduce the risk of cardiovascular disease and premature death at a population level.”

The National Heart, Lung and Blood Institute said: “The major risk factors for a heart attack include smoking, high blood pressure, high cholesterol, overweight and obesity, an unhealthy diet, lack of routine physical activity, high blood sugar due to insulin resistance or diabetes.

“Some of these risk factors such as obesity, high blood pressure and high blood sugar tend to occur together.

“When they do, it’s called metabolic syndrome. In general, a person who has metabolic syndrome is twice as likely to develop heart disease and five times as likely to develop diabetes as someone who doesn’t have metabolic syndrome.”

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Patients with prostate cancer to get pills at home instead of chemotherapy

Recently sufferers had been dealt a double blow of being told they had the killer disease but could not be given treatment. Targeted hormonal therapies enzalutamide and abiraterone will now be temporarily available after new guidance from NHS England. The tablets will allow patients to minimise their risk of infection by staying away from hospitals.

Previously they were only for men who had tried other forms of hormone treatment.

Prostate Cancer UK said about 1,000 men will benefit from the change over the next three months.

The charity’s Heather Blake said: “This is fantastic news for newly diagnosed men. Until now, they have been faced with the distressing prospect that chemotherapy – which could extend their life by 15 months – was not being made available due to the increased risk from Covid-19.”

The Institute of Cancer Research, London, welcomed the move but said it had taken too long. Professor Nick James, who is researching how best to treat prostate cancer, said the drugs were “smarter, kinder treatments”.

Stuart Fraser, 66, who was diagnosed in February, started a petition for the drugs to made available to men in his situation. He is now been prescribed enzalutamide.

The father of two, from Ashtead, Surrey, said: “Being diagnosed was a huge shock. What made it even more worrying was that – because of coronavirus – I was told I couldn’t have the usual treatment of chemotherapy, which would have affected my immune system. That’s why it’s such great news that NHS England have made this change.”

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Vanderpump Rules' Stassi Schroeder Shows Off Her Facial Psoriasis in Makeup-Free Selfie: 'It's a Mood'




"I received a lot of comments like, 'You're so brave.' I'm like, 'No. You know what's brave? Going to war. Posting photos of my psoriasis really isn't that brave.' But I appreciate when people write me and say, 'You just made me feel so much better.' I really love to hear that."

However, Schroeder has since accepted that the psoriasis is a part of her life, saying that she uses comedy to get over her insecurities.

"My greatest strength is my twisted humor. It gets me through everything," she said. "I could be so depressed and heartbroken over someone or something and if I spend time just making it funny or making jokes or making light of it, it fixes everything."

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